Irreversible Cell Injury

   ⇨   Persistence of ischemia  or hypoxia is caused the irreversible cell injury to damage structure and function of cells.

        ⇨  In this stage injured cell can not return to normal .

       

1)    Damage to cell membrane function & plasma membrane :-

                                                        

2)    Calcium Influx:-

Nuclear  change in IRCI:-

 

 Cell death in three conditions-