Irreversible Cell Injury :-
⇨ Persistence of ischemia or hypoxia is caused the irreversible cell injury to damage structure and function of cells.
⇨ In this stage injured cell can not return to normal .
1) Damage to cell membrane function & plasma membrane :-
2) Calcium Influx:-
Nuclear change in IRCI:-
Cell death in three conditions-
Reference-
Robbins basic pathology chapter 1 cellular ageing 9th edition
Textbook of Pathology chapter 3 cellular adaptation and cell injury 8th edition
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